Budesonide

Description

Budesonide is a corticosteroid medication that helps reduce inflammation in the body. It is commonly used to treat conditions such as asthma, allergies, and inflammatory bowel disease. Budesonide works by inhibiting the release of substances in the body that cause inflammation, thereby providing relief from symptoms related to these conditions.

Uses / Indications

• Asthma management
• Chronic obstructive pulmonary disease (COPD)
• Allergic rhinitis (nasal allergies)
• Eosinophilic esophagitis
• Ulcerative colitis
• Crohn’s disease

Dosage and Administration

Adults and children 12 years and older:
Depending on the condition, the typical dose ranges from 200 mcg to 800 mcg, administered once or twice daily by inhalation or as prescribed.

Children aged 6–11 years:
Dosage is typically 100 mcg to 200 mcg once or twice daily, depending on the specific condition and physician recommendations.

Note: Dosage may vary based on medical condition, response to treatment, or doctor’s advice.

How It Works (Mechanism of Action)

Budesonide exerts its effects by binding to glucocorticoid receptors, leading to the inhibition of pro-inflammatory cytokines and mediators. This helps decrease inflammation in the airways and gastrointestinal tract, leading to symptom relief from asthma and other inflammatory conditions.

Side Effects

Common side effects:

• Throat irritation
• Coughing or wheezing
• Headache
• Nausea

Rare/serious side effects:

• Severe allergic reactions (rash, swelling, difficulty breathing)
• Vision changes or cataracts
• Bone fractures (with prolonged use)

Seek medical attention if serious side effects occur.

Precautions / Warnings

• Inform your doctor if you have infections, liver disease, or are pregnant/breastfeeding
• Use caution if combining with other immunosuppressive medications
• Regular monitoring may be required for chronic use

Drug Interactions

May interact with:

• Other corticosteroids
• Certain antifungal medications (e.g., ketoconazole)
• Some medications for epilepsy

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

• Store at room temperature (20°C–25°C / 68°F–77°F)
• Keep away from moisture, heat, and direct light
• Do not freeze
• Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

• Adrenal suppression (fatigue, weakness)
• Rapid weight gain
• Mood changes
• Blurred vision

Contact a poison control center or seek emergency medical help immediately.

Contraindications

• Allergic to Budesonide or any component in the formulation
• Active or untreated infections

Brand Names / Alternatives

• Pulmicort
• Entocort
• Rhinocort
• Generic name: Budesonide