Fluticasone

Description

Fluticasone is a corticosteroid medication used to reduce inflammation and alleviate symptoms associated with various allergic and respiratory conditions. It works by inhibiting inflammatory responses in the body, thus helping to relieve symptoms such as nasal congestion, sneezing, and itchy or runny nose.

Uses / Indications

• Seasonal allergic rhinitis (hay fever)
• Perennial allergic rhinitis
• Chronic obstructive pulmonary disease (COPD) management
• Asthma maintenance therapy
• Nasal polyps treatment
• Inflammation of the skin or scalp (when formulated as a cream or ointment)

Dosage and Administration

Adults and children 12 years and older:
For nasal spray, typically 1-2 sprays in each nostril once daily. For inhalation, usual starting dosage is 88-220 mcg twice daily.

Children aged 4 to 11 years:
For nasal spray, usually 1 spray in each nostril once daily. For inhalation, starting dosage may vary and should be determined by a healthcare provider.

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Fluticasone works by inhibiting the release of inflammatory mediators in the body’s immune response and causing vasoconstriction (narrowing of blood vessels). This action helps decrease inflammation and mitigate symptoms associated with allergic and respiratory conditions.

Side Effects

Common side effects:

• Nasal irritation or burning
• Headache
• Sore throat
• Dry nose or throat

Rare/serious side effects:

• Vision changes (blurred vision, seeing halos around lights)
• Severe allergic reactions (rash, itching, swelling, dizziness)
• Increased risk of infection

Seek medical attention if serious side effects occur.

Precautions / Warnings

• Inform your doctor if you have a history of severe allergies, liver disease, or infections.
• Use caution if combining with other corticosteroids or immunosuppressive medications.
• Regular monitoring is recommended for patients using Fluticasone long-term.

Drug Interactions

May interact with:

• Other corticosteroids (may increase risk of side effects)
• Certain antifungal medications (e.g., ketoconazole)
• Medications that affect liver enzymes

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

• Store at room temperature (20°C–25°C / 68°F–77°F)
• Keep away from moisture, heat, and direct light
• Do not freeze
• Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

• Adrenal suppression symptoms (fatigue, weakness)
• Severe allergic reactions
• Increased blood sugar levels

Contact a poison control center or seek emergency medical help immediately.

Contraindications

• Allergic to Fluticasone or any other ingredient in the formulation
• Active or untreated infections

Brand Names / Alternatives

• Flonase
• Advair (combination inhaler with salmeterol)
• Cutivate (topical)
• Flovent (inhaler)
• Generic name: Fluticasone