Loratadine (Alavert)

Description

Loratadine is a long-acting, non-drowsy antihistamine used to relieve symptoms caused by allergies. It works by blocking histamine, a natural substance your body makes during an allergic reaction.

Uses / Indications

• Seasonal allergic rhinitis (hay fever)
• Perennial allergic rhinitis
• Chronic idiopathic urticaria (persistent hives)
• Sneezing, runny nose, itchy or watery eyes
• Itchy throat or nose
• Skin allergies causing itching or rashes

Dosage and Administration

Adults and children 6 years and older:
10 mg once daily (typically 1 tablet or 10 mL syrup)

Children aged 2–5 years:
5 mg once daily (usually 5 mL syrup or ½ tablet if appropriate)

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Loratadine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and causing allergy symptoms. It doesn’t easily cross the blood-brain barrier, which helps reduce drowsiness.

Side Effects

Common side effects:

• Headache
• Fatigue or drowsiness (less common than older antihistamines)
• Dry mouth
• Stomach discomfort

Rare/serious side effects:

• Fast or irregular heartbeat
• Severe allergic reactions (rash, swelling, dizziness)
• Jaundice (very rare)

Seek medical attention if serious side effects occur.

Precautions / Warnings

• Tell your doctor if you have liver disease, kidney issues, or are pregnant/breastfeeding
• Use caution if combining with other medications that cause drowsiness
• May affect allergy skin testing – discontinue use a few days before testing

Drug Interactions

May interact with:

• Alcohol (may enhance sedative effect)
• Other antihistamines
• Some antibiotics or antifungals (rare)
• Medications that affect liver enzymes

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

• Store at room temperature (20°C–25°C / 68°F–77°F)
• Keep away from moisture, heat, and direct light
• Do not freeze liquid forms
• Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

• Extreme drowsiness
• Fast heartbeat
• Headache
• Nausea

Contact a poison control center or seek emergency medical help immediately.

Contraindications

• Allergic to Loratadine or desloratadine
• Previous serious reaction to antihistamines

Brand Names / Alternatives

• Claritin
• Alavert
• Loridin
• Clarityn (international)
• Generic name: Loratadine