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Amoxicillin

Amoxicillin 250mg, 500mg, 875mg

Amoxicillin is a widely used antibiotic that belongs to the penicillin class of medications. It works by inhibiting the growth of bacteria, making it effective in treating a variety of infections, including those affecting the ears, nose, throat, skin, and urinary tract. Amoxicillin is often prescribed for conditions such as pneumonia, bronchitis, and infections caused by certain strains of bacteria, providing essential relief and aiding in the recovery process.

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Description

Amoxicillin is a broad-spectrum antibiotic used to treat various bacterial infections. It belongs to the penicillin group of drugs and works by inhibiting the growth of bacteria, thereby helping the body to fight off infections effectively.

Uses / Indications

  • Bacterial infections of the ear, nose, and throat
  • Pneumonia and bronchitis
  • Urinary tract infections (UTIs)
  • Skin infections
  • Gastric ulcers caused by Helicobacter pylori (part of combination therapy)
  • Prophylaxis for certain types of endocarditis

Dosage and Administration

Adults:
250 mg to 500 mg every 8 hours, or 500 mg to 875 mg every 12 hours depending on the infection severity.

Children:
Dosing is typically based on the child’s weight (20 mg/kg/day, divided into doses), with a maximum of 1,000 mg per day.

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Amoxicillin works by disrupting the synthesis of bacterial cell walls, leading to the death of susceptible bacteria. This action helps eliminate infections by directly targeting the bacteria causing the illness.

Side Effects

Common side effects:

  • Nausea and vomiting
  • Diarrhea
  • Rash or itching
  • Abdominal pain

Rare/serious side effects:

  • Severe allergic reactions (hives, difficulty breathing, swelling of face/lips)
  • Liver problems (jaundice, dark urine)
  • Severe gastrointestinal problems (persistent diarrhea)

Seek medical attention if serious side effects occur.

Precautions / Warnings

  • Inform your doctor about any allergies, particularly to penicillin or other antibiotics.
  • Use cautiously if you have liver or kidney disease.
  • Injectable form should be administered by a healthcare professional and monitored closely.

Drug Interactions

May interact with:

  • Probenecid (may increase amoxicillin blood levels)
  • Anticoagulants (may increase bleeding risk)
  • Other antibiotics (may decrease efficacy)
  • Certain medications that affect liver enzymes

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

  • Store at room temperature (20°C–25°C / 68°F–77°F)
  • Keep away from moisture, heat, and direct light
  • Shake liquid forms well before use; discard any unused portion after 14 days
  • Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

  • Nausea
  • Vomiting
  • Diarrhea
  • Severe allergic reactions

Contact a poison control center or seek emergency medical help immediately.

Contraindications

  • Allergic to amoxicillin or any penicillin antibiotics
  • History of serious allergic reactions to antibiotics

Brand Names / Alternatives

  • Amoxil
  • Moxatag
  • Trimox
  • Generic name: Amoxicillin