Cefdinir

Cefdinir 300mg

Cefdinir is a broad-spectrum antibiotic belonging to the cephalosporin class, used to treat a variety of bacterial infections, including those affecting the respiratory tract, skin, and urinary system. It works by inhibiting the formation of bacterial cell walls, thereby stopping the growth of bacteria. Commonly prescribed for conditions such as pneumonia, bronchitis, and sinusitis, Cefdinir is effective in providing relief from infection-related symptoms while generally being well-tolerated by patients.

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Description

Cefdinir is a broad-spectrum antibiotic belonging to the cephalosporin class. It is primarily used to treat bacterial infections by inhibiting the synthesis of the bacterial cell wall, effectively leading to the destruction of the bacteria responsible for causing infections.

Uses / Indications

Acute bacterial sinusitis
Acute otitis media (middle ear infection)
Community-acquired pneumonia
Skin and skin structure infections
Chronic bronchitis exacerbations
Streptococcal pharyngitis (strep throat)

Dosage and Administration

Adults and children over 13 years:
600 mg once daily or divided into 300 mg taken twice daily.

Children aged 6 months to 12 years:
Dosing is based on weight, typically 14 mg/kg/day (not exceeding 600 mg) either once daily or in two divided doses.

Note: Dosage may vary based on specific infections, age, and doctor’s advice.

How It Works (Mechanism of Action)

Cefdinir works by disrupting the formation of the bacterial cell wall, which is essential for bacterial growth and replication. By inhibiting penicillin-binding proteins, it ultimately leads to bacterial cell lysis and death.

Side Effects

Common side effects:

Nausea
Diarrhea
Abdominal pain
Headache

Rare/serious side effects:

Severe allergic reactions (rash, itching, swelling)
Clostridium difficile-associated diarrhea
Liver enzyme abnormalities

Seek medical attention if serious side effects occur.

Precautions / Warnings

Inform your doctor if you have a history of kidney disease or liver problems.
Use caution if you have an allergy to penicillin or cephalosporin antibiotics.
Stay hydrated to help prevent potential kidney issues while taking the medication.

Drug Interactions

May interact with:

Antacids containing aluminum or magnesium (may decrease absorption)
Probenecid (may increase cefdinir levels)
Other antibiotics
Medications affecting liver enzymes

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

Store at room temperature (20°C–25°C / 68°F–77°F)
Keep away from moisture, heat, and direct light
Refrigerate liquid forms, and discard after 10 days if not used
Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

Severe nausea and vomiting
Diarrhea
Severe abdominal pain
Drowsiness

Contact a poison control center or seek emergency medical help immediately.

Contraindications

Allergic reactions to cefdinir or other cephalosporins
History of a severe allergic reaction to penicillin

Brand Names / Alternatives

Omnicef
Generic name: Cefdinir