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Doxycycline Hyclate

Doxycycline Hyclate 100mg, 50mg

Doxycycline Hyclate is a broad-spectrum antibiotic that belongs to the tetracycline class, used to treat a variety of bacterial infections, including respiratory tract infections, skin infections, and certain sexually transmitted infections. By inhibiting the growth of bacteria, it helps the body fight off infections effectively. Additionally, it is utilized in the treatment of acne and as a preventive measure against malaria, making it a versatile medication in both acute and chronic infection management.

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Description

Doxycycline Hyclate is a broad-spectrum tetracycline antibiotic used to treat various bacterial infections. It works by inhibiting protein synthesis in bacteria, effectively slowing down their growth and helping the body’s immune system to eradicate the infection.

Uses / Indications

  • Acne vulgaris
  • Respiratory tract infections
  • Urinary tract infections
  • Gonorrhea and chlamydia infections
  • Certain eye infections (e.g., conjunctivitis)
  • Malaria prevention and treatment
  • Anthrax exposure

Dosage and Administration

Adults:
Typically, 100 mg on the first day, followed by 100 mg once daily thereafter, depending on the infection type.

Children (based on weight):
2.2 mg/kg (up to a maximum of 100 mg) on the first day, followed by 2.2 mg/kg (up to a maximum of 100 mg) once daily.

Note: Dosage may vary based on specific infection and doctor’s advice.

How It Works (Mechanism of Action)

Doxycycline Hyclate works by binding to the bacterial ribosome, inhibiting the synthesis of proteins necessary for bacterial growth and reproduction. This action effectively stops the spread of infection, allowing the immune system to eliminate the bacteria.

Side Effects

Common side effects:

  • Nausea or vomiting
  • Diarrhea
  • Sensitivity to sunlight
  • Stomach upset

Rare/serious side effects:

  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Esophageal irritation or ulceration
  • Changes in vision or hearing
  • Severe headache or increased intracranial pressure

Seek medical attention if serious side effects occur.

Precautions / Warnings

  • Inform your doctor if you have liver disease, kidney problems, or a history of allergic reactions to tetracycline antibiotics.
  • Use caution with sun exposure; Doxycycline can increase sensitivity to sunlight.
  • Not recommended for use during pregnancy or in children under the age of 8 due to the risk of teeth discoloration.

Drug Interactions

May interact with:

  • Antacids containing aluminum, calcium, or magnesium (may reduce absorption)
  • Iron supplements (may reduce effectiveness)
  • Certain anticoagulants (blood thinners)
  • Other antibiotics

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

  • Store at room temperature (20°C–25°C / 68°F–77°F)
  • Keep away from moisture, heat, and direct light
  • Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

  • Nausea or vomiting
  • Severe headache
  • Dizziness
  • Diarrhea

Contact a poison control center or seek emergency medical help immediately.

Contraindications

  • Allergic to Doxycycline or other tetracycline antibiotics
  • Pregnant or breastfeeding women

Brand Names / Alternatives

  • Vibramycin
  • Doryx
  • Oracea
  • Monodox
  • Generic name: Doxycycline Hyclate