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Mebendazole

Mebendazole 100mg

Mebendazole is an anti-parasitic medication used to treat a variety of worm infections, including whipworm, hookworm, and pinworm. By inhibiting the growth and reproduction of intestinal parasites, it helps to alleviate symptoms such as abdominal pain and discomfort. Mebendazole is often administered in a chewable tablet or suspension form, making it easy to use for both children and adults, and is generally well-tolerated with minimal side effects.

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Description

Mebendazole is an antihelminthic (anti-worm) medication used to treat a variety of intestinal worm infections. It works by inhibiting the growth and multiplication of parasites in the body, effectively eliminating them through the digestive system.

Uses / Indications

  • Intestinal nematode infections (e.g., roundworms, hookworms, whipworms)
  • Giardiasis (a parasitic infection caused by Giardia)
  • Strongyloidiasis (infection by Strongyloides stercoralis)
  • Enterobiasis (pinworm infection)
  • Neurocysticercosis (tapeworm infection affecting the brain)

Dosage and Administration

Adults and children 2 years and older:
For most infections: 100 mg taken twice daily for 3 days (sometimes a single dose may suffice).

Children under 2 years:
Consult a healthcare provider for appropriate dosing, as it may vary based on the specific condition.

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Mebendazole works by inhibiting the synthesis of microtubules in the intestinal cells of the parasites, disrupting essential functions such as glucose uptake and energy production. This ultimately leads to the death of the worms and their subsequent expulsion from the body through gastrointestinal transit.

Side Effects

Common side effects:

  • Abdominal pain
  • Diarrhea
  • Nausea or vomiting
  • Headache

Rare/serious side effects:

  • Liver dysfunction (elevated liver enzymes)
  • Serious allergic reactions (rash, itching, swelling)
  • Bone marrow suppression (rare)

Seek medical attention if serious side effects occur.

Precautions / Warnings

  • Use caution if you have liver disease or blood disorders
  • Pregnant or breastfeeding women should consult a physician before use
  • Not for use in cases where a complete intestinal obstruction is suspected

Drug Interactions

May interact with:

  • Anticoagulants (blood thinners, may enhance effects)
  • Cimetidine (may increase Mebendazole levels)
  • Other medications affecting liver enzymes

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

  • Store at room temperature (20°C–25°C / 68°F–77°F)
  • Keep away from moisture, heat, and direct light
  • Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

  • Severe abdominal pain
  • Nausea or vomiting
  • Dizziness
  • Unusual tiredness or weakness

Contact a poison control center or seek emergency medical help immediately if overdose is suspected.

Contraindications

  • Allergic to Mebendazole or any of its components
  • Severe liver dysfunction

Brand Names / Alternatives

  • Vermox
  • Emverm
  • Other generic forms available
  • Note: Brand names may vary by country.