Estradiol

Estradiol 1mg, 2mg, 3mg, 4mg, 5mg, 6mg, 7mg, 8mg, 9mg, 10mg, 12mg, 14mg, 16mg, 20mg, 25mg, 30mg, 40mg, 50mg, 60mg, 100mg

Estradiol is a form of estrogen, a hormone that plays a crucial role in the development and maintenance of female reproductive tissues. It is commonly used in hormone replacement therapy to alleviate symptoms associated with menopause, such as hot flashes and vaginal dryness, as well as to support hormonal balance in conditions like hypoestrogenism or certain menstrual disorders. By replenishing estradiol levels, it helps improve overall well-being and quality of life for individuals experiencing hormonal fluctuations.

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Description

Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. It plays a critical role in the development and regulation of the female reproductive system and secondary sexual characteristics. Estradiol is utilized in various medical treatments, including hormone replacement therapy and managing certain hormone-related conditions.

Uses / Indications

Hormone replacement therapy in postmenopausal women
Treatment of hypoestrogenism (low estrogen levels)
Management of menstrual disorders (e.g., irregular periods)
Treatment of certain cancers (e.g., breast cancer in men and advanced prostate cancer)
Relief from menopausal symptoms (e.g., hot flashes, vaginal dryness)
Support in fertility treatments

Dosage and Administration

Adults:
Dosage varies based on the condition being treated; typically, it may range from 0.5 to 2.0 mg daily when used in hormone replacement therapy.

Note: Dosage may vary based on the medical condition and specific doctor’s advice.

How It Works (Mechanism of Action)

Estradiol works by binding to estrogen receptors in various tissues throughout the body, mimicking the effects of naturally occurring estrogen. This action helps regulate the menstrual cycle, maintain bone density, and relieve menopausal symptoms by balancing hormone levels.

Side Effects

Common side effects:

Nausea or vomiting
Headache
Breast tenderness or swelling
Bloating or abdominal discomfort

Rare/serious side effects:

Blood clots or stroke
Severe allergic reactions (rash, itching, swelling)
Jaundice (yellowing of the skin or eyes)

Seek medical attention if serious side effects occur.

Precautions / Warnings

Inform your doctor if you have a history of blood clots, liver disease, or are pregnant/breastfeeding
Regular monitoring may be necessary to evaluate hormone levels
Use caution when combining with other medications that affect hormone levels

Drug Interactions

May interact with:

Anticoagulants (e.g., warfarin)
Anticonvulsants and some antibiotics
Steroids (may increase estrogen effects)
Certain herbal products (e.g., St. John’s Wort)

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

Store at room temperature (20°C–25°C / 68°F–77°F)
Keep away from moisture, heat, and direct light
Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

Severe nausea or vomiting
Unexpected vaginal bleeding or discharge
Headaches
Dizziness or fainting

Contact a poison control center or seek emergency medical help immediately.

Contraindications

Allergic to Estradiol or other estrogen medications
History of hormone-sensitive cancers
Active or history of blood clots

Brand Names / Alternatives

Estrace
Estring
Vivelle-Dot
Femring
Generic name: Estradiol