Olmesartan

Description

Olmesartan is an angiotensin II receptor blocker (ARB) commonly prescribed for managing high blood pressure (hypertension). It works by relaxing blood vessels, enabling blood to flow more easily and reducing the workload on the heart.

Uses / Indications

• High blood pressure (hypertension)
• May be used alone or in combination with other antihypertensive agents
• Prevention of cardiovascular events in high-risk patients (as per physician recommendation)

Dosage and Administration

Adults:
Initial dose is typically 20 mg once daily. The dose may be increased to 40 mg once daily based on blood pressure response.

Pediatric dosing:
Dosage for children (ages 6 and older) should be determined by a physician based on individual assessment.

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Olmesartan selectively blocks the action of angiotensin II at its receptor sites, inhibiting its effects such as vasoconstriction, which helps lower blood pressure. This action also aids in reducing the strain on the heart and helps improve blood flow.

Side Effects

Common side effects:

• Dizziness
• Fatigue
• Headache
• Nausea

Rare/serious side effects:

• Low blood pressure (hypotension)
• Kidney problems (elevated creatinine levels)
• Severe allergic reactions (rash, itching, swelling)

Seek medical attention if serious side effects occur.

Precautions / Warnings

• Notify your doctor if you have a history of kidney disease, liver problems, or dehydration.
• Use with caution if pregnant, planning to become pregnant, or breastfeeding.
• Regular monitoring of blood pressure and kidney function is advised while on this medication.

Drug Interactions

May interact with:

• Diuretics (may enhance hypotensive effect)
• Other antihypertensive medications
• Lithium (may increase lithium levels)
• Non-steroidal anti-inflammatory drugs (NSAIDs)

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

• Store at room temperature (20°C–25°C / 68°F–77°F)
• Keep away from moisture, heat, and direct light
• Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

• Severe dizziness or fainting
• Rapid or irregular heartbeat
• Severe drowsiness
• Nausea or vomiting

Contact a poison control center or seek emergency medical help immediately.

Contraindications

• Allergic to Olmesartan or any of its components
• Pregnant or breastfeeding without medical supervision

Brand Names / Alternatives

• Benicar
• Olmetec (international)
• Generic name: Olmesartan