Valsartan

Description

Valsartan is an angiotensin II receptor blocker (ARB) used primarily for the treatment of high blood pressure (hypertension) and heart failure. It works by relaxing blood vessels, which helps to lower blood pressure and reduce the strain on the heart.

Uses / Indications

• Hypertension (high blood pressure)
• Heart failure
• To reduce the risk of heart attack and stroke in certain patients
• Post-myocardial infarction (to improve survival)

Dosage and Administration

Adults:
Initial dose typically starts at 80 mg once daily. The dose may be adjusted by your doctor depending on your response, with a usual range of 80 mg to 320 mg per day.

Children (6 years and older):
Dosage may vary based on weight and individual needs. Consult your healthcare provider.

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Valsartan selectively blocks the action of angiotensin II, a substance in the body that causes blood vessels to constrict. By inhibiting this action, Valsartan relaxes blood vessels, lowers blood pressure, and improves blood flow to the heart.

Side Effects

Common side effects:

• Dizziness or lightheadedness
• Fatigue
• Headache
• Abdominal pain

Rare/serious side effects:

• Kidney problems (changes in urine output)
• Severe allergic reactions (rash, difficulty breathing)
• Low blood pressure (hypotension)

Seek medical attention if serious side effects occur.

Precautions / Warnings

• Inform your doctor if you have kidney disease, liver problems, or are pregnant/breastfeeding.
• Use caution if you have a history of angioedema (swelling under the skin).
• Monitor blood pressure regularly to avoid hypotension.

Drug Interactions

May interact with:

• Diuretics (water pills)
• Other medications for high blood pressure
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Potassium-sparing diuretics

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

• Store at room temperature (20°C–25°C / 68°F–77°F)
• Keep away from moisture, heat, and direct light
• Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

• Severe dizziness or fainting
• Rapid or irregular heartbeat
• Extreme fatigue

Contact a poison control center or seek emergency medical help immediately.

Contraindications

• Allergic to Valsartan or any component of the formulation
• Pregnant or planning to become pregnant (due to risks to the fetus)

Brand Names / Alternatives

• Diovan
• Valsartan HCTZ (combination with hydrochlorothiazide)
• Generic name: Valsartan