Dicyclomine

Description

Dicyclomine is an anticholinergic medication primarily used to treat the symptoms of irritable bowel syndrome (IBS) and other gastrointestinal disorders. It works by relaxing the muscles in the gut, helping to alleviate cramps and spasms associated with digestive issues.

Uses / Indications

• Irritable bowel syndrome (IBS)
• Spastic colon
• Functional bowel disorders
• Abdominal pain and cramping
• Diarrhea related to GI disorders
• Prior to certain medical examination procedures (e.g., colonoscopy)

Dosage and Administration

Adults:
Start with 20 mg taken three to four times a day. Maintenance doses may be adjusted up to 40 mg taken four times a day based on the doctor’s recommendation.

Children (aged 6 months to 12 years):
Dosage is based on the child’s weight and should be determined by a physician.

Note: Dosage may vary based on individual medical conditions or physician’s advice.

How It Works (Mechanism of Action)

Dicyclomine inhibits acetylcholine at muscarinic receptors in the smooth muscle of the gastrointestinal tract, which decreases muscle spasms and reduces the motility of the intestines.

Side Effects

Common side effects:

• Dry mouth
• Dizziness
• Nausea
• Blurred vision
• Fatigue

Rare/serious side effects:

• Rapid or irregular heartbeat
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Confusion or mental changes

Seek medical attention if serious side effects occur.

Precautions / Warnings

• Inform your doctor if you have a history of urinary retention, glaucoma, or gastrointestinal obstruction.
• Use with caution in elderly patients, who may be more sensitive to side effects.
• Avoid alcohol and other sedatives, as these can increase drowsiness.

Drug Interactions

May interact with:

• Other anticholinergic drugs
• Medications for depression or anxiety
• Certain antihistamines
• Benzodiazepines

Always inform your healthcare provider about any other medications or supplements you are taking.

Storage Instructions

• Store at room temperature (20°C–25°C / 68°F–77°F)
• Keep away from moisture, heat, and direct light
• Ensure that all forms are kept out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

• Severe drowsiness
• Symptoms of hallucination or confusion
• Severe dry mouth and blurred vision
• Rapid heart rate

Contact a poison control center or seek emergency medical help immediately.

Contraindications

• Allergic to Dicyclomine or any component of the formulation
• History of severe intestinal obstruction
• Breastfeeding, as it may affect nursing infants

Brand Names / Alternatives

• Bentyl
• Dicyclomine Hydrochloride