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Lansoprazole

Lansoprazole 15mg, 30mg

Lansoprazole is a proton pump inhibitor (PPI) that is used to treat conditions related to excess stomach acid, such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. By blocking the proton pump in the stomach lining, it effectively reduces the production of stomach acid, providing relief from heartburn and promoting healing of the esophagus and stomach lining. Lansoprazole is commonly prescribed for short-term and long-term management of acid-related disorders, contributing to improved digestive health.

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Description

Lansoprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. It is primarily used to treat conditions that involve excess stomach acid, such as gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome, by blocking the proton pump in the stomach lining.

Uses / Indications

  • Gastroesophageal reflux disease (GERD)
  • Erosive esophagitis (caused by acid reflux)
  • Zollinger-Ellison syndrome (a condition that causes excessive stomach acid production)
  • Peptic ulcers (including those caused by Helicobacter pylori infection)
  • Prevention of ulcers in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs)

Dosage and Administration

Adults:
Typical starting dose is 15 mg to 30 mg taken once daily depending on the condition being treated.

Children:
Dosage varies; consult a physician for specific recommendations based on weight and medical history.

Note: Dosage may vary based on medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Lansoprazole works by inhibiting the hydrogen-potassium ATPase enzyme system (the proton pump) in the stomach lining. This action decreases the production of gastric acid, thereby providing relief from symptoms associated with acid-related conditions.

Side Effects

Common side effects:

  • Nausea or vomiting
  • Diarrhea
  • Constipation
  • Stomach pain

Rare/serious side effects:

  • Severe allergic reactions (rash, swelling, dizziness)
  • Kidney problems (changes in urination)
  • Liver issues (jaundice or dark urine)
  • Bone fractures with long-term use

Seek medical attention if serious side effects occur.

Precautions / Warnings

  • Inform your doctor if you have liver disease, kidney issues, or are pregnant/breastfeeding
  • Long-term use may lead to vitamin B12 deficiency
  • Use caution if combining with other medications

Drug Interactions

May interact with:

  • Clopidogrel (blood thinner)
  • Warfarin (anticoagulant)
  • Certain antifungal medications
  • Medications like methotrexate

Always inform your healthcare provider about any other medications or supplements you’re taking.

Storage Instructions

  • Store at room temperature (15°C–30°C / 59°F–86°F)
  • Keep away from moisture, heat, and direct light
  • Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

  • Severe dizziness
  • Confusion
  • Rapid heart rate
  • Severe gastrointestinal disturbances

Contact a poison control center or seek emergency medical help immediately.

Contraindications

  • Allergic to Lansoprazole or any of its components
  • History of severe allergic reaction to proton pump inhibitors

Brand Names / Alternatives

  • Prevacid
  • Zoton
  • Lansoprazole Delayed-Release Capsules
  • Generic name: Lansoprazole