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Metaxalone

Metaxalone 800mg

Metaxalone is a skeletal muscle relaxant that works by interrupting communication between the nerves and the muscles, helping to relieve pain and discomfort associated with muscle spasms and strains. It is commonly prescribed as part of a comprehensive treatment plan that may include rest, physical therapy, and other measures. Metaxalone is often favored for its relatively lower risk of sedation compared to other muscle relaxants, making it a suitable option for many patients.

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Description

Metaxalone is a centrally acting muscle relaxant indicated for the relief of discomfort associated with acute musculoskeletal conditions. It works by depressing the central nervous system, providing muscle relaxation and decreasing pain perception.

Uses / Indications

  • Muscle spasms caused by injury, strain, or other musculoskeletal conditions
  • Discomfort and pain associated with acute musculoskeletal disorders
  • Adjunctive therapy in the management of other conditions involving muscle tension

Dosage and Administration

Adults:
The usual recommended dosage is 800 mg taken three times daily, with or without food.

Children:
Safety and efficacy have not been established in children under 12 years of age.

Note: Dosage may vary based on individual medical condition or doctor’s advice.

How It Works (Mechanism of Action)

Metaxalone acts primarily on the central nervous system to produce muscle relaxation. The exact mechanism of action is not entirely understood, but it is believed to work by inhibiting excessive reflex activity in the spinal cord and brain, which contributes to muscle spasms and pain.

Side Effects

Common side effects:

  • Drowsiness
  • Dizziness
  • Nausea
  • Gastrointestinal upset

Rare/serious side effects:

  • Allergic reactions (rash, itching, swelling)
  • Jaundice (yellowing of skin or eyes)
  • Severe drowsiness or confusion

Seek medical attention if serious side effects occur.

Precautions / Warnings

  • Inform your doctor if you have liver disease, kidney problems, or a history of substance abuse
  • Use caution when operating heavy machinery or driving
  • May increase the effects of other CNS depressants

Drug Interactions

May interact with:

  • Alcohol (may enhance sedative effects)
  • Benzodiazepines and other muscle relaxants
  • Antidepressants or other medications affecting the CNS

Always inform your healthcare provider about any medications or supplements you are taking.

Storage Instructions

  • Store at room temperature (20°C–25°C / 68°F–77°F)
  • Keep away from moisture and direct light
  • Keep out of reach of children

Missed Dose / Overdose

Missed a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double up.

Overdose symptoms:

  • Severe drowsiness
  • Confusion
  • Nausea or vomiting
  • Respiratory depression (slow or difficult breathing)

Contact a poison control center or seek emergency medical help immediately.

Contraindications

  • Hypersensitivity to Metaxalone or any of its ingredients
  • Severe renal impairment
  • History of drug abuse or dependence

Brand Names / Alternatives

  • Skelaxin
  • Metaxalone (generic)